Direct-to-consumer (DTC) DNA testing has become mainstream! DNA collection kits are now stocking stuffers but, once you know your ancestry, what next?
Did you know you can access and read your raw DNA data at home, and there are also a number of websites that can help analyze your DNA data? To get started you first need to download your raw autosomal, here are instructions for 23andMe, Ancestry DNA, Family Tree DNA, My Heritage, Genes For Good, Vitagene, and Living DNA. Be sure to save your DNA file to a safe location!
If you want to look at the raw data it’s easiest to use a text editor or command line since each file is >700k lines long. Below are 11 websites you can use to help analyze your DNA data;
Promethease is a literature retrieval system that builds a personal DNA report based on connecting a file of DNA genotypes to the scientific findings cited in SNPedia. *Be aware that a Promethease reports on individual SNPs only, yet most traits and diseases are complex and not controlled by a single DNA marker. In Promethease its unknown how all these markers work together, my report contains 265 SNPs with information with breast cancer, do they have cancelling effects or magnifying effects on each other? As they say this report is for educational and research purposes only.
2) DNA Feed
DNA Feed is a tele-genomics/tele-health platform that connects people concerned about their DNA results with licensed genetic counselors.
3) DNA Phenotyping The
HIrisPlex Webtool is easy to use an interactive website to predict eye, hair and skin color from DNA using the IrisPlex, HIrisPlex and HIrisPlex-S systems.
4) GED Match
GEDmatch provides DNA and genealogical analysis tools for amateur and professional researchers and genealogists. Most tools are free, but a few premium tools are available. Several novel tools are offered including an eye color report, are your parents related?, and Archaic DNA matches.
The Eye Color Prediction utility was developed using samples from the GEDmatch database which consists mostly of European descendants.
Are your parents related? ‘Runs of Homozygosity’ (ROH) are large blocks of SNPs where both alleles are the same, there are an indication that your parents each inherited that block from the same ancestor. This analysis looks at ROH in your DNA file and is specifically aimed at determining how closely related your parents might be.
Archaic DNA matches compares your DNA to that of people who lived thousands of years ago.
5) DNA Power
DNApower provides full fitness and nutrition reports, meal plans based on your genetic profile, training plans based on your genetic profile, personal coaching and ongoing support.
6) We Gene
WeGene offers ancestry and trait reports for people of Asian decent.
7) DNA Land
DNA.LAND offers an ancestry analysis that compares your DNA with reference data from different populations to see where in the world your ancestors might have lived. They also offer reports on physical and wellness traits, determined from DNA based on published scientific research, tools for DNA data imputation and a relative-matching feature.
Xcode.Life offers a range of different DNA analysis including lifestyle reports (Fitness, Diet and Nutrition Reports ), skin and allergy reports, health reports, and ancestry composition.
OpenSNP allows customers of direct-to-customer genetic tests to publish their test results, find others with similar genetic variations, learn more about their results, find the latest primary literature on their variations and help scientists to find new associations.
10) Impute Me
Impute Me allows customers to upload their raw genetic data and impute - or 'guess' millions of additional genetic variations that were not measured in the original data. This is done based on overall knowledge of human ethnicity and ancestry.
Impute Me also contains several modules that can perform sophisticated analysis including polygenic risk scoring, a value that gives a summary of many different SNPs - each of which contribute to disease risk.
11) DNA Romance
DNA Romance is a genetic matchmaking site that takes an opposites attract approach to online dating. DNA Romance forecast "Romantic Chemistry" between single people online
by evaluating genes in the Major Histocompatibility Complex (MHC). DNA Romances matches people who are more dissimilar at ~400 alleles positioned across the MHC complex, and high compatability ratings are expected to correlate with the feeling of "Romantic Chemistry" in-person.
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